Atypical natural killer T-cell receptor recognition of CD1d–lipid antigens

Atypical natural killer T-cell receptor recognition of CD1d–lipid antigens

The invariant αβTCR of type I NKT cells recognizes a lipid α-GalCer presented by CD1d. Here the authors describe atypical α-GalCer-reactive NKT cells with diverse TCRs, which bind to CD1d-α-GalCer in a manner distinct from type I NKT cells, thus unveiling greater diversity in lipid antigen recogniti...

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Bibliographic Details
Main Authors: Jérôme Le Nours, T. Praveena, Daniel G. Pellicci, Nicholas A. Gherardin, Fiona J. Ross, Ricky T. Lim, Gurdyal S. Besra, Santosh Keshipeddy, Stewart K. Richardson, Amy R. Howell, Stephanie Gras, Dale I. Godfrey, Jamie Rossjohn, Adam P. Uldrich
Format: Article
Language:English
Published: Nature Portfolio 2016-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10570

Internet

https://doi.org/10.1038/ncomms10570

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