Interleukin-18 cytokine in immunity, inflammation, and autoimmunity: Biological role in induction, regulation, and treatment

Interleukin-18 cytokine in immunity, inflammation, and autoimmunity: Biological role in induction, regulation, and treatment

Interleukin-18 (IL-18) is a potent pro-inflammatory cytokine involved in host defense against infections and regulates the innate and acquired immune response. IL-18 is produced by both hematopoietic and non-hematopoietic cells, including monocytes, macrophages, keratinocytes and mesenchymal cell. I...

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Bibliographic Details
Main Authors: Stella Amarachi Ihim, Sharafudeen Dahiru Abubakar, Zeineb Zian, Takanori Sasaki, Mohammad Saffarioun, Shayan Maleknia, Gholamreza Azizi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
inflammatory diseases
autoimmune diseases
interleukin-18
monoclonal antibodies
immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.919973/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.919973/full

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