Exposure of human cerebral microvascular endothelial cells hCMEC/D3 to laminar shear stress induces vascular protective responses

Exposure of human cerebral microvascular endothelial cells hCMEC/D3 to laminar shear stress induces vascular protective responses

Abstract Endothelial cells (ECs) are constantly submitted in vivo to hemodynamical forces derived from the blood circulation, including shear stress (SS). ECs are able to detect SS and consequently adapt their phenotype, thus affecting many endothelial functions. If a plethora of shear stress-regula...

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Bibliographic Details
Main Authors: Nina Choublier, Meryam Taghi, Marie-Claude Menet, Morgane Le Gall, Johanna Bruce, Philippe Chafey, François Guillonneau, Amélie Moreau, Claire Denizot, Yannick Parmentier, Samir Nakib, Didier Borderie, Haniaa Bouzinba-Segard, Pierre-Olivier Couraud, Sandrine Bourdoulous, Xavier Declèves
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Fluids and Barriers of the CNS
Subjects:
Human endothelial cells
Proteomics
Shear stress
Blood–brain barrier
Brain microvessels
Online Access:https://doi.org/10.1186/s12987-022-00344-w

Internet

https://doi.org/10.1186/s12987-022-00344-w

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