Tox induces T cell IL-10 production in a BATF-dependent manner

Tox is a member of the high mobility group (HMG)-Box transcription factors and plays important roles in thymic T cell development. Outside of the thymus, however, Tox is also highly expressed by CD8 and CD4 T cells in various states of activation and in settings of cancer and autoimmune disease. In...

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Bibliographic Details
Main Authors: D. Alejandro Canaria, J. Alejandra Rodriguez, Luopin Wang, Franklin J. Yeo, Bingyu Yan, Mengbo Wang, Charlotte Campbell, Majid Kazemian, Matthew R. Olson
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1275423/full