The Reciprocal Interaction Between LncRNA CCAT1 and miR-375-3p Contribute to the Downregulation of IRF5 Gene Expression by Solasonine in HepG2 Human Hepatocellular Carcinoma Cells

The Reciprocal Interaction Between LncRNA CCAT1 and miR-375-3p Contribute to the Downregulation of IRF5 Gene Expression by Solasonine in HepG2 Human Hepatocellular Carcinoma Cells

Solasonine (SS), a natural glycoalkaloid component, has been shown to have potent inhibitory activity and cytotoxicity against many cancer types. However, the precise mechanisms underlying this, particularly in hepatocellular carcinoma (HCC) are poorly understood. In this study, we showed that SS in...

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Bibliographic Details
Main Authors: Zheng Liu, ChangJu Ma, XiaoJuan Tang, Qing Tang, LiJie Lou, Yaya Yu, Fang Zheng, JingJing Wu, Xiao-bo Yang, Wei Wang, Swei Sunny Hann
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Oncology
Subjects:
solasonine
HCC
IRF5
lncRNA CCAT1
miR-375-3p
SP1
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01081/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.01081/full

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