CGGBP1-CTCF dynamics in regulation of chromosomal interactions

Genome organisation and gene expression is regulated by specific DNA sequences that include “insulator elements”. Insulator proteins, such as CTCF bind to insulator elements to block spreading of silent chromatin in-cis or inhibit interactions between transcriptional enhancers and promoters. By bind...

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Bibliographic Details
Main Authors: Divyesh Patel, Manthan Patel, Prasoon Agrawal, Umashankar Singh
Format: Article
Language:English
Published: Science Planet Inc. 2017-10-01
Series:Canadian Journal of Biotechnology
Online Access:https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/Special Issue/cjb.2017-a96.pdf