CGGBP1-CTCF dynamics in regulation of chromosomal interactions
Genome organisation and gene expression is regulated by specific DNA sequences that include “insulator elements”. Insulator proteins, such as CTCF bind to insulator elements to block spreading of silent chromatin in-cis or inhibit interactions between transcriptional enhancers and promoters. By bind...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Science Planet Inc.
2017-10-01
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Series: | Canadian Journal of Biotechnology |
Online Access: | https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/Special Issue/cjb.2017-a96.pdf |