Pre-transplantational Control of the Post-transplantational Fate of Human Pluripotent Stem Cell-Derived Cartilage

Summary: Cartilage pellets generated from ectomesenchymal progeny of human pluripotent stem cells (hPSCs) in vitro eventually show signs of commitment of chondrocytes to hypertrophic differentiation. When transplanted subcutaneously, most of the surviving pellets were fully mineralized by 8 weeks. I...

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Bibliographic Details
Main Authors: John Y. Lee, Nadine Matthias, Azim Pothiawala, Bryan K. Ang, Minjung Lee, Jia Li, Deqiang Sun, Sebastien Pigeot, Ivan Martin, Johnny Huard, Yun Huang, Naoki Nakayama
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118302844