Stochastic Boolean model of normal and aberrant cell cycles in budding yeast

Abstract The cell cycle of budding yeast is governed by an intricate protein regulatory network whose dysregulation can lead to lethal mistakes or aberrant cell division cycles. In this work, we model this network in a Boolean framework for stochastic simulations. Our model is sufficiently detailed...

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Bibliographic Details
Main Authors: Kittisak Taoma, John J. Tyson, Teeraphan Laomettachit, Pavel Kraikivski
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-024-00452-3