The role of metabolic reprogramming of tumor-associated macrophages in shaping the immunosuppressive tumor microenvironment

The role of metabolic reprogramming of tumor-associated macrophages in shaping the immunosuppressive tumor microenvironment

Macrophages are potent immune effector cells in innate immunity and exert dual-effects in the tumor microenvironment (TME). Tumor-associated macrophages (TAMs) make up a significant portion of TME immune cells. Similar to M1/M2 macrophages, TAMs are also highly plastic, and their functions are regul...

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Bibliographic Details
Main Authors: Lunxu Li, Yu Tian
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Tumor-associated macrophage
Tumor microenvironment
Metabolism
Immunosuppression
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223002925

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http://www.sciencedirect.com/science/article/pii/S0753332223002925

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