Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells

Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells

Dynamic post-translational modification of RNA polymerase II (RNAPII) coordinates the co-transcriptional recruitment of enzymatic complexes that regulate chromatin states and processing of nascent RNA. Extensive phosphorylation of serine residues at the largest RNAPII subunit occurs at its structura...

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Bibliographic Details
Main Authors: João D Dias, Tiago Rito, Elena Torlai Triglia, Alexander Kukalev, Carmelo Ferrai, Mita Chotalia, Emily Brookes, Hiroshi Kimura, Ana Pombo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-12-01
Series:eLife
Subjects:
transcription cycle
post-transcriptional modification
RNA polymerase II
C-terminal domain
methylation
non-histone protein lysine methylation
Online Access:https://elifesciences.org/articles/11215

Internet

https://elifesciences.org/articles/11215

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