An Aptamer-Based Biosensor for the Azole Class of Antifungal Drugs

An Aptamer-Based Biosensor for the Azole Class of Antifungal Drugs

ABSTRACT This technical report describes the development of an aptamer for sensing azole antifungal drugs during therapeutic drug monitoring. Modified synthetic evolution of ligands through exponential enrichment (SELEX) was used to discover a DNA aptamer recognizing azole class antifungal drugs. Th...

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Bibliographic Details
Main Authors: Gregory R. Wiedman, Yanan Zhao, Arkady Mustaev, Jinglei Ping, Ramya Vishnubhotla, A. T. Charlie Johnson, David S. Perlin
Format: Article
Language:English
Published: American Society for Microbiology 2017-08-01
Series:mSphere
Subjects:
antifungals
aptamers
graphene
biosensors
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00274-17

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https://journals.asm.org/doi/10.1128/mSphere.00274-17

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