Enhanced immune responses following heterologous vaccination with self-amplifying RNA and mRNA COVID-19 vaccines.

Enhanced immune responses following heterologous vaccination with self-amplifying RNA and mRNA COVID-19 vaccines.

The optimal vaccination strategy to boost responses in the context of pre-existing immune memory to the SARS-CoV-2 spike (S) glycoprotein is an important question for global public health. To address this, we explored the SARS-CoV-2-specific humoral and cellular immune responses to a novel self-ampl...

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Bibliographic Details
Main Authors: Tamara Elliott, Hannah M Cheeseman, Abbey B Evans, Suzanne Day, Leon R McFarlane, Jessica O'Hara, Mohini Kalyan, Fahimah Amini, Tom Cole, Alan Winston, Sarah Fidler, Katrina M Pollock, James A Harker, Robin J Shattock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010885

Internet

https://doi.org/10.1371/journal.ppat.1010885

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