Successful induction of diabetes in mice demonstrates no gender difference in development of early diabetic retinopathy.

<h4>Purpose</h4>Female mice have been found to be resistant to streptozotocin (STZ)-induced diabetes, and pre-clinical research related to diabetic complications commonly omits females. The purpose of this study was to develop a method to induce diabetes in female mice, and to determine...

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Bibliographic Details
Main Authors: Aicha Saadane, Emma M Lessieur, Yunpeng Du, Haitao Liu, Timothy S Kern
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0238727