CD83 expressed by macrophages is an important immune checkpoint molecule for the resolution of inflammation

CD83 expressed by macrophages is an important immune checkpoint molecule for the resolution of inflammation

Excessive macrophage (Mφ) activation results in chronic inflammatory responses or autoimmune diseases. Therefore, identification of novel immune checkpoints on Mφ, which contribute to resolution of inflammation, is crucial for the development of new therapeutic agents. Herein, we identify CD83 as a...

Full description

Bibliographic Details
Main Authors: Katrin Peckert-Maier, Pia Langguth, Astrid Strack, Lena Stich, Petra Mühl-Zürbes, Christine Kuhnt, Christina Drassner, Elisabeth Zinser, Marius Wrage, Jochen Mattner, Alexander Steinkasserer, Dmytro Royzman, Andreas B. Wild
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
CD83
macrophages
checkpoint molecule
resolution of inflammation
STAT-6
wound healing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1085742/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1085742/full

Similar Items