Ephexin3/ARHGEF5 Together with Cell Migration Signaling Partners within the Tumor Microenvironment Define Prognostic Transcriptional Signatures in Multiple Cancer Types

Ephexin3/ARHGEF5 Together with Cell Migration Signaling Partners within the Tumor Microenvironment Define Prognostic Transcriptional Signatures in Multiple Cancer Types

Cancer cell migration involves a repertoire of signaling proteins that lead cytoskeleton reorganization as a critical step in metastatic dissemination. RhoGEFs are multidomain effectors that integrate signaling inputs to activate the molecular switches that orchestrate actin cytoskeleton reorganizat...

Full description

Bibliographic Details
Main Authors: Dante Gustavo Juan-Guadarrama, Yarely Mabell Beltrán-Navarro, Guadalupe Reyes-Cruz, José Vázquez-Prado
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
Ephexin3
Rho guanine nucleotide exchange factor (RhoGEF)
cancer signaling signature
cancer datasets mining
TCGA
DepMap
Online Access:https://www.mdpi.com/1422-0067/24/22/16427

Internet

https://www.mdpi.com/1422-0067/24/22/16427

Similar Items