Pathophysiological profile of non-ventilated lung injury in healthy female pigs undergoing mechanical ventilation

Abstract Background Lung regions excluded from mechanical insufflation are traditionally assumed to be spared from ventilation-associated lung injury. However, preliminary data showed activation of potential mechanisms of injury within these non-ventilated regions (e.g., hypoperfusion, inflammation)...

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Bibliographic Details
Main Authors: Elena Spinelli, Anna Damia, Francesco Damarco, Beatrice Gregori, Federica Occhipinti, Zara Busani, Marco Leali, Michele Battistin, Caterina Lonati, Zhanqi Zhao, Alessandra Maria Storaci, Gianluca Lopez, Valentina Vaira, Stefano Ferrero, Lorenzo Rosso, Stefano Gatti, Tommaso Mauri
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-024-00449-3