Divalent magnesium restores cytoskeletal storage lesions in cold-stored platelet concentrates
Abstract Cold storage of platelet concentrates (PC) has become attractive due to the reduced risk of bacterial proliferation, but in vivo circulation time of cold-stored platelets is reduced. Ca2+ release from storage organelles and higher activity of Ca2+ pumps at temperatures < 15 °C triggers c...
Main Authors: | Konstanze Aurich, Jan Wesche, Martin Ulbricht, Oliver Otto, Andreas Greinacher, Raghavendra Palankar |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-10231-x |
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