Mechanical evolution of DNA double-strand breaks in the nucleosome.
Double strand breaks (DSB) in the DNA backbone are the most lethal type of defect induced in the cell nucleus by chemical and radiation treatments of cancer. However, little is known about the outcomes of damage in nucleosomal DNA, and on its effects on damage repair. We performed microsecond-long m...
| 主要な著者: | , , |
|---|---|
| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
Public Library of Science (PLoS)
2018-06-01
|
| シリーズ: | PLoS Computational Biology |
| オンライン･アクセス: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006224&type=printable |