Fe-catalyzed Decarbonylative Alkylative Spirocyclization of <i>N</i>-Arylcinnamamides: Access to Alkylated 1-Azaspirocyclohexadienones

Fe-catalyzed Decarbonylative Alkylative Spirocyclization of <i>N</i>-Arylcinnamamides: Access to Alkylated 1-Azaspirocyclohexadienones

For the convenient introduction of simple linear/branched alkyl groups into biologically important azaspirocyclohexadienones, a practical Fe-catalyzed decarbonylative cascade spiro-cyclization of <i>N</i>-aryl cinnamamides with aliphatic aldehydes to provide alkylated 1-azaspiro-cyclohex...

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Bibliographic Details
Main Authors: Xiang Peng, Ren-Xiang Liu, Xiang-Yan Xiao, Luo Yang
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
decarbonylation
alkylation
spirocyclization
aldehyde
cinnamamide
Online Access:https://www.mdpi.com/1420-3049/25/3/432

Internet

https://www.mdpi.com/1420-3049/25/3/432

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