Huntingtin-associated protein 1-associated intracellular trafficking in neurodegenerative diseases

Huntingtin-associated protein 1 (HAP1), the first identified HTT-binding partner, is highly expressed in the central nervous system, and has been found to associated with neurological diseases. Mounting evidence suggests that HAP1 functions as a component of cargo-motor molecules to bind various pro...

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Bibliographic Details
Main Authors: Xingxing Chen, Enhao He, Chonglin Su, Yan Zeng, Jiang Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1100395/full