Identification and characterization of naturally occurring splice variants of SAMHD1

<p>Abstract</p> <p>Background</p> <p>Sterile Alpha Motif and HD domain-containing protein 1 (SAMHD1) is a recently identified host factor that restricts HIV-1 replication in dendritic and myeloid cells. SAMHD1 is a dNTPase that presumably reduces the cellular dNTP level...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Welbourn Sarah, Miyagi Eri, White Tommy E, Diaz-Griffero Felipe, Strebel Klaus
Format: Artikel
Sprache:English
Veröffentlicht: BMC 2012-10-01
Schriftenreihe:Retrovirology
Schlagworte:
Online Zugang:http://www.retrovirology.com/content/9/1/86