Oxidative stress generated by polycyclic aromatic hydrocarbons from ambient particulate matter enhance vascular smooth muscle cell migration through MMP upregulation and actin reorganization

Abstract Background Epidemiological studies have suggested that elevated concentrations of particulate matter (PM) are strongly associated with the incidence of atherosclerosis, however, the underlying cellular and molecular mechanisms of atherosclerosis by PM exposure and the components that are ma...

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Bibliographic Details
Main Authors: Sujin Ju, Leejin Lim, Young-Jae Ki, Dong-Hyun Choi, Heesang Song
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Particle and Fibre Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s12989-022-00472-z