The expression of glucocorticoid and mineralocorticoid receptors in pituitary tumors causing Cushing’s disease and silent corticotroph tumors

The expression of glucocorticoid and mineralocorticoid receptors in pituitary tumors causing Cushing’s disease and silent corticotroph tumors

ObjectivePituitary neuroendocrine corticotroph tumors commonly cause Cushing’s disease (CD) that results from increased adrenocorticotropic hormone (ACTH) secretion by the pituitary tumor and consequent increase of cortisol levels in blood. However, in some patients, corticotroph tumors remain clini...

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Bibliographic Details
Main Authors: Paulina Kober, Natalia Rusetska, Beata J. Mossakowska, Maria Maksymowicz, Monika Pękul, Grzegorz Zieliński, Andrzej Styk, Jacek Kunicki, Łukasz Działach, Przemysław Witek, Mateusz Bujko
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Endocrinology
Subjects:
pituitary neuroendocrine tumor (PitNET)
Cushing’s disease (CD)
silent corticotroph adenoma
NR3C1
NR3C2
hypothalamic - pituitary - adrenal axis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1124646/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1124646/full

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