Revealing posttranscriptional regulatory elements through network-level conservation.

We used network-level conservation between pairs of fly (Drosophila melanogaster/D. pseudoobscura) and worm (Caenorhabditis elegans/C. briggsae) genomes to detect highly conserved mRNA motifs in 3' untranslated regions. Many of these elements are complementary to the 5' extremity of known...

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Bibliographic Details
Main Authors: Chang S Chan, Olivier Elemento, Saeed Tavazoie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1309705?pdf=render