Iron – a key nexus in the virulence of Aspergillus fumigatus

Iron is an essential but in excess toxic nutrient. Therefore, fungi evolved fine-tuned mechanisms for uptake and storage of iron, such as the production of siderophores (low-molecular mass iron-specific chelators). In Aspergillus fumigatus, iron starvation causes extensive transcriptional remodeling...

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Bibliographic Details
Main Author: Hubertus eHaas
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00028/full