SGLT‐2 inhibitors enhance the effect of metformin to ameliorate hormonal changes and inflammatory markers in a rat PCOS model

SGLT‐2 inhibitors enhance the effect of metformin to ameliorate hormonal changes and inflammatory markers in a rat PCOS model

Abstract Polycystic ovary syndrome (PCOS) is a common endocrine, reproductive, and metabolic disorder affecting females. The management of PCOS is challenging and current interventions are not enough to deal with all consequences of this syndrome. We explored the beneficial effect of combined sodium...

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Bibliographic Details
Main Authors: Manal Moustafa Mahmoud, Laila Ahmed Rashed, Somia Abdulatif Soliman, Safaa Mostafa Sayed, Omneya Kamel, Samaa Samir Kamar, Rania El Sayed Hussien
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Physiological Reports
Subjects:
AMPKα‐SIRT1
empagliflozin
insulin resistance
metformin
PCOS
Online Access:https://doi.org/10.14814/phy2.15858

Internet

https://doi.org/10.14814/phy2.15858

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