Copper(II) Complexes with Carnosine Conjugates of Hyaluronic Acids at Different Dipeptide Loading Percentages Behave as Multiple SOD Mimics and Stimulate Nrf2 Translocation and Antioxidant Response in In Vitro Inflammatory Model

Copper(II) Complexes with Carnosine Conjugates of Hyaluronic Acids at Different Dipeptide Loading Percentages Behave as Multiple SOD Mimics and Stimulate Nrf2 Translocation and Antioxidant Response in In Vitro Inflammatory Model

A series of copper(II) complexes with the formula [Cu<sup>2+</sup>Hy(<i>x</i>)Car%] varying the molecular weight (MW) of Hyaluronic acid (Hy, <i>x</i> = 200 or 700 kDa) conjugated with carnosine (Car) present at different loading were synthesized and characterized...

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Bibliographic Details
Main Authors: Francesco Bellia, Valeria Lanza, Irina Naletova, Barbara Tomasello, Valeria Ciaffaglione, Valentina Greco, Sebastiano Sciuto, Pietro Amico, Rosanna Inturri, Susanna Vaccaro, Tiziana Campagna, Francesco Attanasio, Giovanni Tabbì, Enrico Rizzarelli
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Antioxidants
Subjects:
copper
carnosine
hyaluronic acid
conjugates
antioxidant
SOD
Online Access:https://www.mdpi.com/2076-3921/12/8/1632

Internet

https://www.mdpi.com/2076-3921/12/8/1632

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