Protection of Hippocampal CA1 Neurons Against Ischemia/Reperfusion Injury by Exercise Preconditioning via Modulation of Bax/ Bcl-2 Ratio and Prevention of Caspase-3 Activation

Introduction: Ischemia leads to loss of neurons by apoptosis in specific brain regions, especially in the hippocampus. The purpose of this study was investigating the effects of exercise preconditioning on expression of Bax, Bcl-2, and caspase-3 proteins in hippocampal CA1 neurons after induction of...

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Bibliographic Details
Main Authors: Nahid Aboutaleb, Nabi Shamsaei, Hamid Rajabi, Mehdi Khaksari, Sohaila Erfani, Farnaz Nikbakht, Pezhman Motamedi, Ali Shahbazi
Format: Article
Language:English
Published: Iran University of Medical Sciences 2016-01-01
Series:Basic and Clinical Neuroscience
Subjects:
Online Access:http://bcn.iums.ac.ir/browse.php?a_code=A-10-766-1&slc_lang=en&sid=1