A Comprehensive In Silico Analysis of Deleterious SNPs of Paraplegin Protein Associated with Hereditary Spastic Paraplegia through Mitochondrial Dysfunction
Hereditary spastic paraplegia (HSP) is a heterogenous neurological disorder primarily associated with progressive spasticity. Paraplegin is a mitochondrial protein and mutations in this protein can lead to HSP. In this study, in silico analysis was carried out to identify the pathogenic variants of...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
University of Management and Technology
2020-06-01
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| Series: | Bioscientific Review |
| Subjects: | |
| Online Access: | https://journals.umt.edu.pk/index.php/BSR/article/view/398 |