CB2 receptor agonist JWH133 activates AMPK to inhibit growth of C6 glioma cells

It has been reported that endocannabinoid receptor type 2 (CB2) agonist JWH133 inhibits the growth of C6 glioma cells, but the underlying mechanism has not yet been fully elucidated. We showed that JWH133 inhibited C6 cells growth, reduced cAMP production and inhibited PKA activity through CB2 recep...

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Bibliographic Details
Main Authors: Wang Feng, Wang Jing, Zhao Tong, Zhang Yi, Li Qian
Format: Article
Language:English
Published: De Gruyter 2019-07-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2019-0041