The killing effect of Tanshinol on breast cancer cells: insight into the reversion of TGF-β1-mediated suppression of NK cell functions

The killing effect of Tanshinol on breast cancer cells: insight into the reversion of TGF-β1-mediated suppression of NK cell functions

Background: Natural killer (NK) cells play an indispensable role in anti-tumor immunity. TGF-β1 is the main accomplice of tumor immune escape, inhibiting tumor immunity mediated by NK cells. It is reported that Salvia miltiorrhiza can promote the immune killing effect of NK cells. In this study, Tan...

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Bibliographic Details
Main Authors: Chunmei Yang, Cheng Qian, Tingting Zhang, Weiwei Zheng, Shan Zhang, Shijun Wang, Aiyun Wang, Yang Zhao, Yin Lu
Format: Article
Language:English
Published: IMR Press 2021-11-01
Series:Frontiers in Bioscience-Landmark
Subjects:
tanshinol
tumor
tgf-β1
nkg2d
dap10
nk cell functions
Online Access:https://www.imrpress.com/journal/FBL/26/11/10.52586/5013

Internet

https://www.imrpress.com/journal/FBL/26/11/10.52586/5013

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