Reversed Proteolysis—Proteases as Peptide Ligases

Historically, ligase activity by proteases was theoretically derived due to their catalyst nature, and it was experimentally observed as early as around 1900. Initially, the digestive proteases, such as pepsin, chymotrypsin, and trypsin were employed to perform in vitro syntheses of small peptides....

Full description

Bibliographic Details
Main Author: Peter Goettig
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Catalysts
Subjects:
Online Access:https://www.mdpi.com/2073-4344/11/1/33