Validation of N Protein Antibodies to Diagnose Previous SARS-CoV-2 Infection in a Large Cohort of Healthcare Workers: Use of Roche Elecsys<sup>®</sup> Immunoassay in the S Protein Vaccination Era

Validation of N Protein Antibodies to Diagnose Previous SARS-CoV-2 Infection in a Large Cohort of Healthcare Workers: Use of Roche Elecsys<sup>®</sup> Immunoassay in the S Protein Vaccination Era

The aim of this study was to validate the detection of anti-nucleocapsid protein (N protein) antibodies for the diagnosis of SARS-CoV-2 infection in light of the fact that most COVID-19 vaccines use the spike (S) protein as the antigen. Here, 3550 healthcare workers (HCWs) were enrolled from May 202...

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Bibliographic Details
Main Authors: Juan Francisco Delgado, Mònica Vidal, Germà Julià, Gema Navarro, Rosa María Serrano, Eva van den Eynde, Marta Navarro, Joan Calvet, Jordi Gratacós, Mateu Espasa, Pilar Peña
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Viruses
Subjects:
SARS-CoV-2
antibody response
infection
vaccination
nucleocapsid protein
spike protein
Online Access:https://www.mdpi.com/1999-4915/15/4/930

Internet

https://www.mdpi.com/1999-4915/15/4/930

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