Kinetic studies on the reaction between dicyanocobinamide and hypochlorous acid.

Hypochlorous acid (HOCl) is a potent oxidant generated by myeloperoxidase (MPO), which is an abundant enzyme used for defense against microbes. We examined the potential role of HOCl in corrin ring destruction and subsequent formation of cyanogen chloride (CNCl) from dicyanocobinamide ((CN)2-Cbi). S...

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Bibliographic Details
Main Authors: Dhiman Maitra, Iyad Ali, Rasha M Abdulridha, Faten Shaeib, Sana N Khan, Ghassan M Saed, Subramaniam Pennathur, Husam M Abu-Soud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4222763?pdf=render