cGAS-STING pathway in cancer biotherapy

cGAS-STING pathway in cancer biotherapy

Abstract The activation of the cGAS-STING pathway has tremendous potential to improve anti-tumor immunity by generating type I interferons. In recent decades, we have witnessed that producing dsDNA upon various stimuli is an initiative factor, triggering the cGAS-SING pathway for a defensive host. T...

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Bibliographic Details
Main Authors: Yang Wang, Jingwen Luo, Aqu Alu, Xuejiao Han, Yuquan Wei, Xiawei Wei
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Molecular Cancer
Subjects:
cGAS-STING pathway
Cancer biotherapy
Interferon
Cyclic dinucleotide
Agonist
Delivery system
Online Access:http://link.springer.com/article/10.1186/s12943-020-01247-w

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http://link.springer.com/article/10.1186/s12943-020-01247-w

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