cGAS-STING pathway in cancer biotherapy
Abstract The activation of the cGAS-STING pathway has tremendous potential to improve anti-tumor immunity by generating type I interferons. In recent decades, we have witnessed that producing dsDNA upon various stimuli is an initiative factor, triggering the cGAS-SING pathway for a defensive host. T...
Main Authors: | Yang Wang, Jingwen Luo, Aqu Alu, Xuejiao Han, Yuquan Wei, Xiawei Wei |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-09-01
|
Series: | Molecular Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12943-020-01247-w |
Similar Items
-
Emerging mechanisms and implications of cGAS-STING signaling in cancer immunotherapy strategies
by: Jiawen Zhang, et al.
Published: (2024-01-01) -
cGAS‐STING signaling in cancer: Regulation and therapeutic targeting
by: Xinzou Fan, et al.
Published: (2023-09-01) -
The cGAS-STING pathway in COPD: targeting its role and therapeutic potential
by: Kexin Liao, et al.
Published: (2024-08-01) -
Porcine cGAS-STING signaling induced autophagy inhibits STING downstream IFN and apoptosis
by: Nengwen Xia, et al.
Published: (2022-10-01) -
Comprehensive elaboration of the cGAS-STING signaling axis in cancer development and immunotherapy
by: Juyan Zheng, et al.
Published: (2020-08-01)