Effects of Poria cocos extract on metabolic dysfunction-associated fatty liver disease via the FXR/PPARα-SREBPs pathway

Effects of Poria cocos extract on metabolic dysfunction-associated fatty liver disease via the FXR/PPARα-SREBPs pathway

Despite the increase in the global prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD), no approved drug currently exists for the disease. Poria cocos (Schw.) Wolf (P. cocos) is a medicinal mushroom belonging to a family of polyporaceae widely used in TCM clinics to protect th...

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Bibliographic Details
Main Authors: Jinbiao He, Yu Yang, Fan Zhang, Yanjuan Li, Xiaosi Li, Xuemei Pu, Xudong He, Mei Zhang, Xinxing Yang, Qiuman Yu, Yan Qi, Xuefang Li, Jie Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
MAFLD (metabolic-associated fatty liver disease)
Poria cocos (Schw.) Wolf.
bile acid metabolism
FXR/PPARα-SREBP pathway
lipid homeostasis
UPLC Q-TOF/MS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1007274/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1007274/full

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