Impact of CYP3A5 Status on the Clinical and Financial Outcomes Among African American Kidney Transplant Recipients

Impact of CYP3A5 Status on the Clinical and Financial Outcomes Among African American Kidney Transplant Recipients

Background. Pharmacogenetic profiling of transplant recipients demonstrates that the marked variation in the metabolism of immunosuppressive medications, particularly tacrolimus, is related to genetic variants. Patients of African ancestry are less likely to carry loss-of-function (LoF) variants in...

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Bibliographic Details
Main Authors: Joy Obayemi, MD, Brendan Keating, PhD, Lauren Callans, MD, Krista L. Lentine, MD, PhD, Mark A. Schnitzler, PhD, Yasar Caliskan, MD, Huiling Xiao, MA, Vikas R. Dharnidharka, MD, Roslyn B. Mannon, MD, David A. Axelrod, MD, MBA
Format: Article
Language:English
Published: Wolters Kluwer 2022-10-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001379

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http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001379

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