Heterologous Booster Immunization Based on Inactivated SARS-CoV-2 Vaccine Enhances Humoral Immunity and Promotes BCR Repertoire Development

Heterologous Booster Immunization Based on Inactivated SARS-CoV-2 Vaccine Enhances Humoral Immunity and Promotes BCR Repertoire Development

Recent studies have indicated that sequentially administering SARS-CoV-2 vaccines can result in increased antibody and cellular immune responses. In this study, we compared homologous and heterologous immunization strategies following two doses of inactivated vaccines in a mouse model. Our research...

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Bibliographic Details
Main Authors: Xinghang Li, Fengyuan Zeng, Rong Yue, Danjing Ma, Ziyan Meng, Qi Li, Zhenxiao Zhang, Haobo Zhang, Yuansheng Liao, Yun Liao, Guorun Jiang, Heng Zhao, Li Yu, Dandan Li, Ying Zhang, Longding Liu, Qihan Li
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Vaccines
Subjects:
SARS-CoV-2
vaccine
sequential immunization
B-cell receptor
humoral immunity
Online Access:https://www.mdpi.com/2076-393X/12/2/120

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https://www.mdpi.com/2076-393X/12/2/120

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