Tilianin improves cognition in a vascular dementia rodent model by targeting miR-193b-3p/CaM- and miR-152-3p/CaMKIIα-mediated inflammatory and apoptotic pathways

Tilianin improves cognition in a vascular dementia rodent model by targeting miR-193b-3p/CaM- and miR-152-3p/CaMKIIα-mediated inflammatory and apoptotic pathways

IntroductionAlthough vascular dementia (VaD) is the second most prevalent form of dementia, there is currently a lack of effective treatments. Tilianin, isolated from the traditional drug Dracocephalum moldavica L., may protect against ischemic injury by inhibiting oxidative stress and inflammation...

Full description

Bibliographic Details
Main Authors: Ting Sun, Linjie Tan, Mimin Liu, Li Zeng, Kaiyue Zhao, Zhongdi Cai, Shengnan Sun, Zhuorong Li, Rui Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
calcium/calmodulin-dependent kinase II
calmodulin
inflammation
microRNA-152-3p
microRNA-193b-3p
tilianin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1118808/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1118808/full

Similar Items