Familial Linkage and Association of the <i>NR3C1</i> Gene with Type 2 Diabetes and Depression Comorbidity

Familial Linkage and Association of the <i>NR3C1</i> Gene with Type 2 Diabetes and Depression Comorbidity

Impairment in the hypothalamic-pituitary-adrenal (HPA) axis and cortisol pathway may be major contributing factors to the common pathogenesis of major depressive disorders (MDD) and type 2 diabetes (T2D). A significant player in the neuroendocrine HPA axis and cortisol response is the glucocorticoid...

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Bibliographic Details
Main Authors: Mutaz Amin, Shumail Syed, Rongling Wu, Teodor Tudorel Postolache, Claudia Gragnoli
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
nuclear receptor subfamily 3 group C member
<i>NR3C1</i>
glucocorticoid receptor
GR
major depressive disorder
MDD
Online Access:https://www.mdpi.com/1422-0067/23/19/11951

Internet

https://www.mdpi.com/1422-0067/23/19/11951

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