Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush

Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush

Abstract We previously found that global deletion of the mitochondrial enzyme arginase 2 (A2) limits optic nerve crush (ONC)-induced neuronal death. Herein, we examined the cell-specific role of A2 in this pathology by studies using wild type (WT), neuronal-specific calbindin 2 A2 KO (Calb2cre/+ A2...

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Main Authors: Syed A. H. Zaidi, Zhimin Xu, Tahira Lemtalsi, Porsche Sandow, Sruthi Athota, Fang Liu, Stephen Haigh, Yuqing Huo, S. Priya Narayanan, David J. R. Fulton, Modesto A. Rojas, Abdelrahman Y. Fouda, Robert W. Caldwell, Ruth B. Caldwell
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06180-6

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https://doi.org/10.1038/s41419-023-06180-6

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