Comparative clinical significance and biological roles of PFKFB family members in oral squamous cell carcinoma

Abstract Background Cancer cells promote glycolysis, which supports rapid cell growth and proliferation. Phosphofructokinase-fructose bisphosphatases (PFKFBs), a family of bidirectional glycolytic enzymes, play key roles in the regulation of glycolysis in many types of cancer. However, their roles i...

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Bibliographic Details
Main Authors: Kai-Fang Hu, Chih-Wen Shu, Cheng-Hsin Lee, Ching-Jiunn Tseng, Yu-Hsiang Chou, Pei-Feng Liu
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-023-03110-6