Profiling Virus-Specific Tcf1+ T Cell Repertoires During Acute and Chronic Viral Infection

Profiling Virus-Specific Tcf1+ T Cell Repertoires During Acute and Chronic Viral Infection

CD8 T cells play a crucial role in providing protection from viral infections. It has recently been established that a subset of CD8 T cells expressing Tcf1 are responsible for sustaining exhausted T cells during chronic lymphocytic choriomeningitis virus (LCMV) infection. Many of these studies, how...

Full description

Bibliographic Details
Main Authors: Alexander Yermanos, Ioana Sandu, Alessandro Pedrioli, Mariana Borsa, Franziska Wagen, Nathalie Oetiker, Suzanne P. M. Welten, Katharina Pallmer, Sai T. Reddy, Annette Oxenius
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
viral infection
deep sequencing
TCF1
TCR sequencing
adaptive immune receptor repertoire sequencing
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00986/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00986/full

Similar Items