Comparative Immunohistochemical Analysis of Ochratoxin A Tumourigenesis in Rats and Urinary Tract Carcinoma in Humans; Mechanistic Significance of p-S6 Ribosomal Protein Expression

Comparative Immunohistochemical Analysis of Ochratoxin A Tumourigenesis in Rats and Urinary Tract Carcinoma in Humans; Mechanistic Significance of p-S6 Ribosomal Protein Expression

Ochratoxin A (OTA) is considered to be a possible human urinary tract carcinogen, based largely on a rat model, but no molecular genetic changes in the rat carcinomas have yet been defined. The phosphorylated-S6 ribosomal protein is a marker indicating activity of the mammalian target of rapamycin,...

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Bibliographic Details
Main Authors: Sarah Pinder, Peter Mantle, Diana Herman, Cheryl Gillett, Patrycja Gazinska
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:Toxins
Subjects:
ochratoxin A
phospho-S6 ribosomal protein
mycotoxin
renal cell carcinoma
transitional cell carcinoma
testicular cancer
angiosarcoma
Balkan endemic nephropathy
food safety
DNA adducts
Online Access:http://www.mdpi.com/2072-6651/4/9/643

Internet

http://www.mdpi.com/2072-6651/4/9/643

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