Advances in ultrasound-targeted microbubble-mediated gene therapy for liver fibrosis

Advances in ultrasound-targeted microbubble-mediated gene therapy for liver fibrosis

Hepatic fibrosis develops as a wound-healing scar in response to acute and chronic liver inflammation and can lead to cirrhosis in patients with chronic hepatitis B and C. The condition arises due to increased synthesis and reduced degradation of extracellular matrix (ECM) and is a common pathologic...

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Bibliographic Details
Main Authors: Cuiyuan Huang, Hong Zhang, Ruidan Bai
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Liver fibrosis
Ultrasound-targeted microbubbles
Gene therapy
Gene delivery
Cavitation
Sonoporation
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383516303045

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http://www.sciencedirect.com/science/article/pii/S2211383516303045

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