A Multidrug Approach to Modulate the Mitochondrial Metabolism Impairment and Relative Oxidative Stress in Fanconi Anemia Complementation Group A

A Multidrug Approach to Modulate the Mitochondrial Metabolism Impairment and Relative Oxidative Stress in Fanconi Anemia Complementation Group A

Fanconi Anemia (FA) is a rare recessive genetic disorder characterized by aplastic anemia due to a defective DNA repair system. In addition, dysfunctional energy metabolism, lipid droplets accumulation, and unbalanced oxidative stress are involved in FA pathogenesis. Thus, to modulate the altered me...

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Bibliographic Details
Main Authors: Enrico Cappelli, Nadia Bertola, Silvia Bruno, Paolo Degan, Stefano Regis, Fabio Corsolini, Barbara Banelli, Carlo Dufour, Silvia Ravera
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Metabolites
Subjects:
fanconi anemia
fatty acid synthesis
lipid accumulation
mitochondrial metabolism
oxidative stress
quercetin
Online Access:https://www.mdpi.com/2218-1989/12/1/6

Internet

https://www.mdpi.com/2218-1989/12/1/6

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