Lung specific homing of diphenyleneiodonium chloride improves pulmonary fibrosis by inhibiting macrophage M2 metabolic program

Lung specific homing of diphenyleneiodonium chloride improves pulmonary fibrosis by inhibiting macrophage M2 metabolic program

Introduction: Pulmonary fibrosis (PF) is a fatal disease with a variable and unpredictable course. Effective clinical treatment for PF remains a challenge due to low drug accumulation in lungs and imbalanced polarization of pro/anti-fibrotic macrophages. Objectives: To identify the alteration of imm...

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Bibliographic Details
Main Authors: Huirui Wang, Yinghui Gao, Li Wang, Yang Yu, Jiaozhen Zhang, Chunyu Liu, Yaxin Song, Haochuan Xu, Jingcheng Wang, Hongxiang Lou, Ting Dong
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Journal of Advanced Research
Subjects:
Lung fibrosis
Diphenyleneiodonium chloride
Imaging mass spectrometry
Chemical proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123222001084

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http://www.sciencedirect.com/science/article/pii/S2090123222001084

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