Petiveria alliacea L. extract protects against streptozotocin-induced type-2 diabetes by modulating the cAMP/PKA/CREB/cFOS pathway

Petiveria alliacea L. extract protects against streptozotocin-induced type-2 diabetes by modulating the cAMP/PKA/CREB/cFOS pathway

Objective: This study was designed to investigate the nephroprotective effect and mechanism of action of a methanolic extract of Petiveria alliacea leaves (MEPAL) in streptozotocin-induced diabetic nephropathy (DN) in rats. Methods: Twenty-five Wistar rats were randomly distributed into five groups....

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Bibliographic Details
Main Authors: Oluwafemi Adeleke Ojo, Olufimihan Abolade, Akingbolabo Daniel Ogunlakin, Christopher Oloruntoba Akintayo, Olaoluwa Sesan Olukiran, Olalekan Elijah Odesanmi, Omolola Adenike Ajayi-Odoko, Adebola Busola Ojo, Basiru Olaitan Ajiboye, Samuel Olatunde Dahunsi
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Phytomedicine Plus
Subjects:
Nephroprotection
Medicinal plants
Oxidative stress
Apoptosis
Metabolic syndrome
Online Access:http://www.sciencedirect.com/science/article/pii/S266703132400071X

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http://www.sciencedirect.com/science/article/pii/S266703132400071X

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