Depletion of ATP and Oxidative Stress Underlie Zinc-Induced Cell Injury

The mechanisms of cell injury resulting in a special type of cell death combining the features of apoptosis and necrosis were examined in Hep-2 cells exposed to 300 μM zinc sulfate during 24h. Acute exposure to zinc induced a rapid rise in metallothionein levels and increased oxidative stress occurr...

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Bibliographic Details
Main Author: Emil Rudolf
Format: Article
Language:English
Published: Karolinum Press 2007-01-01
Series:Acta Medica
Subjects:
Online Access:https://actamedica.lfhk.cuni.cz/50/1/0043/